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US Patent 11859015 Immunogenic WT-1 peptides and methods of use thereof

Patent 11859015 was granted and assigned to Memorial Sloan Kettering Cancer Center on January, 2024 by the United States Patent and Trademark Office.

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 US Patent 11859015 Immunogenic WT-1 peptides and methods of use thereof

Article

Patent abstract

This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT1-expressing cancer, comprising heteroclitic peptides derived from the WT-1 protein.

Infobox
Is a
Patent
Patent
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Patent Applicant
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center
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Current Assignee
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
118590150
Patent Inventor Names
David A. Scheinberg0
Tao Dao0
Date of Patent
January 2, 2024
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Patent Application Number
170074150
Date Filed
August 31, 2020
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Patent Citations
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US Patent 7115272 Compositions and methods for WT1 specific immunotherapy
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US Patent 7144581 Compositions and methods for WT1 specific immunotherapy
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US Patent 7323181 Compositions and methods for WT1 specific immunotherapy
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US Patent 7329410 Compositions and method for WT1 specific immunotherapy
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US Patent 7368119 Compositions and methods for WT1 specific immunotherapy
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US Patent 7420034 HLA-A24-restricted cancer antigen peptides
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US Patent 7488718 Synthetic HLA binding peptide analogues and uses thereof
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US Patent 7517950 Tumor antigen based on products of the tumor suppressor gene WT1
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US Patent 7553494 WT1 fusion proteins
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US Patent 7597894 Compositions and methods employing alternative reading frame polypeptides for the treatment of cancer and infectious disease
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US Patent 7598221 Synthetic HLA binding WT-1 peptide analogues and uses thereof
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US Patent 7608685 Tumor antigen based on products of the tumor suppressor gene WT1
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US Patent 7655249 Compositions and methods for WT1 specific immunotherapy
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US Patent 7662386 Compositions and methods for WT1 specific immunotherapy
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US Patent 7666985 HLA-A24-restricted cancer antigen peptides
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US Patent 7745391 Human thrombospondin polypeptide
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US Patent 7807792 Tumor antigen based on products of the tumor suppressor gene WT1
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US Patent 7833775 Modified free-living microbes, vaccine compositions and methods of use thereof
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US Patent 7901693 Compositions and methods for WT1 specific immunotherapy
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US Patent 7915393 Compositions and methods for WT1 specific immunotherapy
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US Patent 7939627 Peptides comprising an epitope of the wilms tumor gene product
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US Patent 8071732 Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
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US Patent 8105604 WT1 modified peptide
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US Patent 8216595 Powerful vaccine composition comprising lipopeptide and poly I:C as an adjuvant
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US Patent 8288355 siRNA specific to WT1 17AA(−)isoform and use thereof
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US Patent 8529904 Immunotherapeutic methods using epitopes of WT-1 and GATA-1
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US Patent 8557247 Lyophilised antigen composition
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US Patent 8735357 Method of inducing antigen-specific T cells
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US Patent 8765687 WT1 HLA class II-binding peptides and compositions and methods comprising same
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US Patent 8771702 Non-hemolytic LLO fusion proteins and methods of utilizing same
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US Patent 8778350 Method of treating cancer with an HLA-A*3303-restricted WT1 peptide and pharmaceutical composition comprising the same
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US Patent 8920776 Compositions and methods for the detection diagnosis and therapy of hematological malignancies
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US Patent 9045556 Therapeutic agent for cancer
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US Patent 9181302 WT1 antigen peptide conjugate vaccine
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US Patent 9216205 Modified polynucleotides encoding granulysin
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US Patent 9226955 Allogeneic autophagosome-enriched composition for the treatment of disease
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US Patent 9233149 WT1 HLA class II—binding peptides and compositions and methods comprising same
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US Patent 9248173 WT1 antigen peptide conjugate vaccine
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US Patent 9265816 Immunogenic WT-1 peptides and methods of use thereof
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US Patent 9266932 Cancer antigen helper peptide
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US Patent 9272026 HLA-A*1101-restricted WT1 peptide and pharmaceutical composition comprising the same
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US Patent 9403886 Tumor antigen based on products of the tumor suppressor gene WT1
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US Patent 9499602 Non-hemolytic LLO fusion proteins and methods of utilizing same
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US Patent 9518126 Vaccine comprising monocyte or immature myeloid cells (IMC) which were loaded with the ligand of natural killer T cell and antigen
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US Patent 6861234 Method of epitope discovery
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US Patent 7030212 Tumor antigen based on products of the tumor suppressor gene WT1
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US Patent 7063854 Composition and methods for WTI specific immunotherapy
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Patent Primary Examiner
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Daniel C Gamett
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