Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 22, 2016
Patent Application Number
14163269
Date Filed
February 12, 2014
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides recombinant proteins or peptides comprising a mutated listeriolysin O (LLO) protein or fragment thereof, comprising a substitution or internal deletion of the cholesterol-binding domain or a portion thereof, fusion proteins or peptides comprising same, nucleotide molecules encoding same, and vaccine vectors comprising or encoding same. The present invention also provides methods of utilizing recombinant proteins, peptides, nucleotide molecules, and vaccine vectors of the present invention to induce an immune response to a peptide of interest.
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