Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Roger Norcross
Eric Andre Kusznir
Annick Goergler
Fabian Dey
Date of Patent
October 17, 2023
Patent Application Number
17576582
Date Filed
January 14, 2022
Patent Citations
Patent Citations Received
0
Patent Primary Examiner
Patent abstract
The present invention provides selected dihydrobenzimidazolones which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and alter the substrate specificity of the CRBN E3 ubiquitin ligase complex, resulting in breakdown of intrinsic downstream proteins. The disclosed compounds are useful for the treatment of cancer.
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