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US Patent 11780923 PD-L1 antibody, antigen-binding fragment thereof and medical application thereof

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Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11780923
Patent Inventor Names
Shaoyu Xu
Qiyue Hu
Dongbing Cui
Xiangdong Qu
Weikang Tao
Piaoyang Sun
Guoqing Cao
Houcong Jin
...
Date of Patent
October 10, 2023
Patent Application Number
16947583
Date Filed
August 7, 2020
Patent Citations
‌
US Patent 9334331 Bispecific antibodies
‌
US Patent 11359021 PD-L1 antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
‌
US Patent 8617546 Anticancer agent comprising anti-PD-1 antibody or anti-PD-L1 antibody
‌
US Patent 10421807 Interleukin-31 monoclonal antibody
Patent Primary Examiner
‌
Lynn A Bristol
CPC Code
‌
C07K 2317/565
‌
C07K 2317/24
‌
C07K 16/28
‌
A61K 2039/505
‌
A61K 39/39558
Patent abstract

The present invention relates to a PD-L1 antibody, antigen-binding fragments, and medical application thereof. Further, the present invention relates to chimeric antibodies and humanized antibodies comprising the CDR regions of the present PD-L1 antibody, as well as a pharmaceutical composition comprising the present PD-L1 antibody and the antigen-binding fragments thereof, and their use as anti-cancer drugs. In particular, the present invention relates to a humanized PD-L1 antibody and its use in preparation of a medicament for the treatment of PD-L1 mediated disease or disorder.

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