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US Patent 9334331 Bispecific antibodies

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Contents

Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9334331
Date of Patent
May 10, 2016
Patent Application Number
13885421
Date Filed
November 17, 2011
Patent Citations Received
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US Patent 12133867 Universal anti-CD22 chimeric antigen receptor engineered immune cells
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US Patent 12122840 Method of modifying isoelectric point of antibody via amino acid substitution in CDR
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US Patent 12129297 Antibodies against TIM3 and uses thereof
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US Patent 12129300 Antibody variable domains targeting the NKG2D receptor
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US Patent 11667709 Anti-TIGIT antibodies and methods of use
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US Patent 11680101 Anti-OPG antibodies
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US Patent 11753469 Methods of using bispecific CD33 and CD3 binding proteins
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US Patent 11760795 Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and uses thereof for treating cancer cachexia and cancer
...
Patent Primary Examiner
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Michael Szperka
Patent abstract

Various bispecific antibodies that specifically bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X and functionally substitute for the cofactor function of blood coagulation factor VIII, that is, the function to promote activation of blood coagulation factor X by activated blood coagulation factor IX, were produced. From these antibodies, multispecific antigen-binding molecules having a high activity of functionally substituting for blood coagulation factor VIII were successfully discovered.

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