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US Patent 11427563 Aryl cyclopropyl-amino-isoquinolinyl amide compounds

Patent 11427563 was granted and assigned to Aerie Pharmaceuticals on August, 2022 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Aerie Pharmaceuticals

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Current Assignee

Aerie Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Andriy Kornilov0

Mitchell A. deLong0

Jill M. Sturdivant0

Cynthia L. Lichorowic0

Date of Patent

August 30, 2022

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Patent Application Number

165708490

Date Filed

September 13, 2019

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Patent Citations

US Patent 10112920 Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds

US Patent 10174017 Dual mechanism inhibitors for the treatment of disease

US Patent 10858339 Aryl cyclopropyl-amino-isoquinolinyl amide compounds

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US Patent 10899714 6-aminoisoquinoline compounds

US Patent 10882840 Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds

US Patent 10654844 Dual mechanism inhibitors for the treatment of disease

Patent Citations Received

US Patent 11891376 Aryl cyclopropyl-amino-isoquinolinyl amide compounds

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US Patent 11707460 Ophthalmic compositions

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Patent Primary Examiner

D Margaret M Seaman

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CPC Code

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Provided herein are amino isoquinolinyl amide and sulfonamide compounds that affect the function of kinases and other proteins in a cell and that are useful as therapeutic agents. In particular, these compounds are useful in the treatment of eye diseases such as glaucoma and retinal diseases, as anti-inflammatory agents, for the treatment of cardiovascular diseases, and for diseases characterized by abnormal growth, such as cancers.

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