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US Patent 10174017 Dual mechanism inhibitors for the treatment of disease

Patent 10174017 was granted and assigned to Aerie Pharmaceuticals on January, 2019 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Current Assignee
Aerie Pharmaceuticals
Aerie Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10174017
Date of Patent
January 8, 2019
Patent Application Number
15924089
Date Filed
March 16, 2018
Patent Citations Received
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US Patent 12090087 Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir
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US Patent 11938057 Hydrodynamically actuated preservative free dispensing system
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US Patent 12018012 Aryl cyclopropyl-amino-isoquinolinyl amide compounds
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US Patent 10472327 6-aminoisoquinoline compounds
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US Patent 10532993 Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
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US Patent 10568878 Combination therapy
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US Patent 10583038 Piezoelectric dispenser with replaceable ampoule
...
Patent Primary Examiner
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D Margaret M Seaman
Patent abstract

Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (IOP) may be achieved.

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