US Patent 11234993 Method for treatment of cellular senescence
Patent 11234993 was granted and assigned to National Yang-Ming University on February, 2022 by the United States Patent and Trademark Office.
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Patent abstract
The present invention provides an alcohol extract of Ajuga taiwanensis Nakai ex Murata exhibits significant effects on inhibiting the senescence in human WI-38 lung fibroblasts and human dermal fibroblasts. Moreover, the alcohol extract of A. taiwanensis is able to suppress the expression of the cofilin-1, a protein involved in actin dynamics and cell morphology and found to be increased in senescent cells. Suppression effect of cell senescence by this herb extract is more efficient in mild concentration without over-inhibition of cell viability and growth.
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Patent Inventor Names
Bing-Ze Lin0
Cheng-Han Tsai0
Chun-Yuan Chang0
Chung-Sheng Huang0
Pin-Ho Lo0
Wei-Hsiang Hsu0
Yi-Jang Lee0
Yuan-Heng Tu0
Yun-Lian Lin0
Edits on 21 May, 2023
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Patent Number
112349930
Date of Patent
February 1, 2022
0Patent Application Number
168833800
Date Filed
May 26, 2020
0Official Website
Patent Primary Examiner
Edits on 8 Jun, 2022
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US Patent 11234993 Method for treatment of cellular senescence
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
11234993
Date of patent
February 1, 2022
Patent application number
16883380
Date Filed
May 26, 2020
Patent primary examiner
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