Log in
Sign up
Golden has been acquired by ComplyAdvantage.Read about it here ⟶
‌

US Patent 11014927 Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators

Patent 11014927 was granted and assigned to FORMA Therapeutics on May, 2021 by the United States Patent and Trademark Office.

OverviewStructured DataIssuesContributorsActivity

All edits

Edits on 12 Dec, 2023
"Add patent abstract"
Golden AI profile picture
Golden AI
edited on 12 Dec, 2023
Edits made to:
Article (+391 characters)
Article

Patent abstract

The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds of formula (I) useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.

Edits on 23 May, 2023
"Remove website redirecting to Patent Public Search front page"
Golden AI profile picture
Golden AI
edited on 23 May, 2023
Edits made to:
Infobox (-1 properties)
Infobox
Official Website
https://pdfpiw.uspto.gov/.piw?Docid=1101492700
Edits on 28 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 28 Apr, 2023
Edits on 26 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 26 Apr, 2023
Edits on 24 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 24 Apr, 2023
Edits on 23 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 23 Apr, 2023
Edits on 22 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 22 Apr, 2023
Edits on 5 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 5 Apr, 2023
Edits on 4 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 4 Apr, 2023
Edits on 3 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 3 Apr, 2023
Edits on 2 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 2 Apr, 2023
Edits on 2 Apr, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 2 Apr, 2023
"Entity importer update"
Golden AI profile picture
Golden AI
edited on 1 Apr, 2023
Infobox
Is a
Patent
Patent
0
Patent Applicant
FORMA Therapeutics
FORMA Therapeutics
0
Current Assignee
FORMA Therapeutics
FORMA Therapeutics
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
110149270
Date of Patent
May 25, 2021
0
Patent Application Number
164962790
Date Filed
March 20, 2018
0
Official Website
https://pdfpiw.uspto.gov/.piw?Docid=110149270
Patent Citations
‌
US Patent 10004725 Methods of treatment
0
‌
US Patent 10017491 Compounds and uses thereof for the modulation of hemoglobin
0
‌
US Patent 10034879 Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation
0
‌
US Patent 10077249 Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde
0
‌
US Patent 10100040 Compounds and uses thereof for the modulation of hemoglobin
0
‌
US Patent 10100043 Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
0
‌
US Patent 10208052 Compositions for activating pyruvate kinase
0
‌
US Patent 10266551 Compounds and uses thereof for the modulation of hemoglobin
0
‌
US Patent 10315991 Compounds and uses thereof for the modulation of hemoglobin
0
‌
US Patent 10377741 Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
0
‌
US Patent 10450269 Compounds and uses thereof for the modulation of hemoglobin
0
‌
US Patent 10435393 Compounds and uses thereof for the modulation of hemoglobin
0
‌
US Patent 10472371 Compositions for activating pyruvate kinase
0
‌
US Patent 10493035 Tablets comprising 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
0
‌
US Patent 10577345 Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde
0
‌
US Patent 10675274 Activating pyruvate kinase R
0
‌
US Patent 10683285 Modulators of hemoglobin
0
‌
US Patent 10695330 Methods of treatment
0
Patent Primary Examiner
‌
Taylor V Oh
0
Edits on 27 Mar, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 27 Mar, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 27 Mar, 2023
Edits on 24 Mar, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 24 Mar, 2023
Edits on 22 Mar, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 22 Mar, 2023
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 22 Mar, 2023
Edits on 28 Sep, 2022
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 28 Sep, 2022
Edits on 27 Sep, 2022
"update citations for inverse infoboxes"
Golden AI profile picture
Golden AI
edited on 27 Sep, 2022

Find more entities like US Patent 11014927 Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators

Use the Golden Query Tool to find similar entities by any field in the Knowledge Graph, including industry, location, and more.
Open Query Tool
Access by API
Golden Query Tool
Golden logo
By using this site, you agree to our Terms of Service.