Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Saulius Klimasauskas0
Giedrius Vilkaitis0
Milda Mickute0
Date of Patent
May 18, 2021
0Patent Application Number
155596890
Date Filed
March 18, 2016
0Patent Primary Examiner
Patent abstract
Provided is a method for modifying a ssRNA at the 3′ end, the method including contacting the strand with a ssRNA 2′-O-methyltransferase in the presence of a co-factor, under conditions which allow for the transfer by the ssRNA 2′-O-methyltransferase of a part of the co-factor onto the 3′ end of the ssRNA to form a modified ssRNA, wherein the ssRNA bears 2′-OH group at 3′ terminal nucleotide and wherein the part of the co-factor transferred includes a reporter group or a functional group.
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