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US Patent 10953000 Combination of pimavanserin and cytochrome P450 modulators

Patent 10953000 was granted and assigned to Acadia Pharmaceuticals on March, 2021 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Current Assignee
Acadia Pharmaceuticals
Acadia Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
109530000
Patent Inventor Names
Andrew Parkinson0
Date of Patent
March 23, 2021
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Patent Application Number
160876040
Date Filed
March 23, 2017
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Patent Citations
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US Patent 10449185 Formulations of pimavanserin
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US Patent 10646480 Formulations of pimavanserin
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US Patent 10525046 Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
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US Patent 10028944 Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
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US Patent 10517860 Combination of pimavanserin and cytochrome P450 modulators
Patent Citations Received
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US Patent 11840515 Methods for preparing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form c
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US Patent 11648242 Pharmaceutical composition comprising pimavanserin, process of preparation and use thereof
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US Patent 11464768 Pimavanserin alone or in combination for use in the treatment of Alzheimer's disease psychosis
Patent Primary Examiner
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Sarah Pihonak
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Patent abstract

A method for treating a disease or disorder in a patient who is currently taking a cytochrome P450 inhibitor comprising administering to the patient a dose of pimavanserin or a pharmaceutical acceptable salt thereof, wherein the dose is at least 20% lower than a dose of pimavanserin or a pharmaceutical acceptable salt thereof that would otherwise have been recommended to the patient if the patient were not currently taking the cytochrome P450 inhibitor.

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