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US Patent 10517860 Combination of pimavanserin and cytochrome P450 modulators

Patent 10517860 was granted and assigned to Acadia Pharmaceuticals on December, 2019 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Patent Applicant

Acadia Pharmaceuticals

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Current Assignee

Acadia Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Andrew Parkinson0

Date of Patent

December 31, 2019

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Patent Application Number

163791690

Date Filed

April 9, 2019

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Patent Citations

US Patent 10028944 Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases

Patent Citations Received

US Patent 11840515 Methods for preparing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form c

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US Patent 10953000 Combination of pimavanserin and cytochrome P450 modulators

US Patent 10981870 Methods for preparing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form

US Patent 10981871 Methods for preparing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form C

US Patent 11464768 Pimavanserin alone or in combination for use in the treatment of Alzheimer's disease psychosis

US Patent 10849891 Formulations of pimavanserin

Patent Primary Examiner

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Patent abstract

A method for treating a disease or disorder in a patient who is currently taking a cytochrome P450 inhibitor comprising administering to the patient a dose of pimavanserin or a pharmaceutical acceptable salt thereof, wherein the dose is at least 20% lower than a dose of pimavanserin or a pharmaceutical acceptable salt thereof that would otherwise have been recommended to the patient if the patient were not currently taking the cytochrome P450 inhibitor.

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