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US Patent 10947183 Fenfluramine compositions and methods of preparing the same

Patent 10947183 was granted and assigned to Zogenix International Limited on March, 2021 by the United States Patent and Trademark Office.

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Patent abstract

Methods of preparing a fenfluramine active pharmaceutical ingredient are provided. Aspects of the method include (a) hydrolyzing a 2-(3-(trifluoromethyl)phenyl)acetonitrile composition to produce a 2-(3-(trifluoromethyl)phenyl)acetic acid composition; (b) reacting the 2-(3-(trifluoromethyl)phenyl)acetic acid composition with acetic anhydride and a catalyst to produce a 1-(3-(trifluoromethyl)phenyl)propan-2-one composition; and

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Patent Citations Received
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US Patent 11786487 Formulation for inhibiting formation of 5-HT
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Patent Citations Received
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US Patent 11759440 Formulation for inhibiting formation of 5-HT
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Official Website
https://pdfpiw.uspto.gov/.piw?Docid=1094718300
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Patent Citations Received
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US Patent 11634377 Fenfluramine compositions and methods of preparing the same
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Patent Citations Received
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US Patent 11458111 Ketogenic diet compatible fenfluramine formulation
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Patent citations received
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US Patent 11406606 Formulation for inhibiting formation of 5-HT2B agonists and methods of using same
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 US Patent 10947183 Fenfluramine compositions and methods of preparing the same

Infobox
Is a
Patent
Patent
Patent applicant
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Zogenix International Limited
Current assignee
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Zogenix International Limited
Patent jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent number
10947183
Date of patent
March 16, 2021
Patent application number
16431391
Date Filed
June 4, 2019
Patent citations
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US Patent 10351509 Fenfluramine compositions and methods of preparing the same
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US Patent 10351510 Fenfluramine compositions and methods of preparing the same
Patent primary examiner
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Clinton A Brooks

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