Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Marc W. Andersen0
Derek J. Londesbrough0
Date of Patent
July 16, 2019
0Patent Application Number
153855250
Date Filed
December 20, 2016
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Methods of preparing a fenfluramine active pharmaceutical ingredient are provided. Aspects of the method include (a) hydrolyzing a 2-(3-(trifluoromethyl)phenyl)acetonitrile composition to produce a 2-(3-(trifluoromethyl)phenyl)acetic acid composition; (b) reacting the 2-(3-(trifluoromethyl)phenyl)acetic acid composition with acetic anhydride and a catalyst to produce a 1-(3-(trifluoromethyl)phenyl)propan-2-one composition; and
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