The present disclosure provides methods to increase the percentage of edited yeast cells in a cell population using nucleic-acid guided editing, and automated multi-module instruments for performing these methods.

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US Patent 11787841 Rationally-designed mutations to the thrA gene for enhanced lysine production in

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Eileen Spindler0

Krishna Kannan0

Miles Gander0

Paul Hardenbol0

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US Patent 11746347 Simultaneous multiplex genome editing in yeast

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https://pdfpiw.uspto.gov/.piw?Docid=109273850

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US Patent 11667932 Electroporation modules and instrumentation

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edited on 30 Apr, 2023

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US Patent 11634719 Curing for recursive nucleic acid-guided cell editing

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US Patent 11299731 CRISPR editing to embed nucleic acid landing pads into genomes of live cells

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US Patent 11306327 Nucleic acid-guided nucleases

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US Patent 11286471 Cascade/dCas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells

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US Patent 11359187 Cascade/dCas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells

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US Patent 11274296 Simultaneous multiplex genome editing in yeast

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US Patent 11306298 Mad nucleases

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US Patent 11407994 Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells via viral delivery

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US Patent 11332850 Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells

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US Patent 11352621 HTP genomic engineering platform

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US Patent 11591592 Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells using microcarriers

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