Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Patent Inventor Names
Chi-Fang Wu0
Jeffry D. Watkins0
John D. Mendlein0
Minh-Ha Do0
Ying Buechler0
Darin Lee0
Kristi Piehl0
Kyle P. Chiang0
...
Date of Patent
November 12, 2019
0Patent Application Number
161222310
Date Filed
September 5, 2018
0Patent Citations
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The present invention provides histidyl-tRNA synthetase and Fc region conjugate polypeptides (HRS-Fc conjugates), such as HRS-Fc fusion polypeptides, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The HRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified HRS polypeptides.
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