Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Chi-Fang Wu0
Marc Thomas0
Minh-Ha Do0
Ying Buechler0
Darin Lee0
Jeffry D. Watkins0
John D. Mendlein0
Kristi Piehl0
...
Date of Patent
October 9, 2018
Patent Application Number
15415369
Date Filed
January 25, 2017
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The present invention provides histidyl-tRNA synthetase and Fc region conjugate polypeptides (HRS-Fc conjugates), such as HRS-Fc fusion polypeptides, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The HRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified HRS polypeptides.
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