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US Patent 10457980 Multiplex labeling of molecules by sequential hybridization barcoding

Patent 10457980 was granted and assigned to California Institute of Technology on October, 2019 by the United States Patent and Trademark Office.

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US Patent 12116626 AP50 polymerases and uses thereof

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US Patent 12110548 Bi-directional in situ analysis

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US Patent 12104151 Systems and methods for determining nucleic acids

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US Patent 12071667 Sequence analysis using meta-stable nucleic acid molecules

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US Patent 12060603 Methods for internally controlled in situ assays using padlock probes

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US Patent 11959075 Systems and methods for determining nucleic acids

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Patent abstract

The present invention, among other things, provides technologies for detecting and/or quantifying nucleic acids in cells, tissues, organs or organisms. In some embodiments, through sequential barcoding, the present invention provides methods for high-throughput profiling of a large number of targets, such as transcripts and/or DNA loci.

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Patent Inventor Names

Ahmet Coskun0

Chang Ho Sohn0

Eric Lubeck0

Long Cai0

Sheel Shah0

Timur Zhiyentayev0

Ting-Fang He0

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US Patent 11753674 Methods and systems for determining spatial patterns of biological targets in a sample

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US Patent 11713485 Hybridization chain reaction methods for in situ molecular detection

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US Patent 11639518 Compositions and methods for analyte detection

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US Patent 11359228 Methods and systems for determining spatial patterns of biological targets in a sample

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US Patent 11566277 Compositions and methods for analyte detection

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US Patent 11618918 Methods and systems for determining spatial patterns of biological targets in a sample

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Is a

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Patent Applicant

California Institute of Technology

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Current Assignee

California Institute of Technology

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

104579800

Date of Patent

October 29, 2019

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Patent Application Number

144357350

Date Filed

April 30, 2014

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Patent Citations Received

US Patent 11286515 Methods and systems for determining spatial patterns of biological targets in a sample

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US Patent 11299774 Spatially distinguished, multiplex nucleic acid analysis of biological specimens

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US Patent 11352667 Nucleic acid sequencing

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US Patent 11359228 Methods and systems for determining spatial patterns of biological targets in a sample

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US Patent 11390912 Spatially distinguished, multiplex nucleic acid analysis of biological specimens

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US Patent 11473129 Multiplex labeling of molecules by sequential hybridization barcoding

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US Patent 11555219 Method of detecting target nucleic acid molecules

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US Patent 11566277 Compositions and methods for analyte detection

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US Patent 11597965 RNA templated ligation

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Patent Primary Examiner

Ethan C. Whisenant

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US Patent 11286515 Methods and systems for determining spatial patterns of biological targets in a sample

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US Patent 11390912 Spatially distinguished, multiplex nucleic acid analysis of biological specimens

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Patent Citations Received

US Patent 11597965 RNA templated ligation

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