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US Patent 10377764 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors

Patent 10377764 was granted and assigned to Karus Therapeutics on August, 2019 by the United States Patent and Trademark Office.

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Is a
Patent
Patent

Patent attributes

Patent Applicant
Karus Therapeutics
Karus Therapeutics
Current Assignee
Karus Therapeutics
Karus Therapeutics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10377764
Date of Patent
August 13, 2019
Patent Application Number
15753361
Date Filed
August 19, 2016
Patent Citations
‌
US Patent 10035785 Phosphoinositide 3-kinase inhibitors
Patent Citations Received
‌
US Patent 11779586 Compounds comprising tricyclic heterocyclic compounds
‌
US Patent 10668077 Compositions comprising phosphoinositide 3-kinase inhibitors and a second antiproliferative agent
‌
US Patent 11708378 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
0
Patent Primary Examiner
‌
Bruck Kifle
Patent abstract

The invention relates to a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein each R3 is independently selected from H, halo, fluorinated C1-C10 alkyl, —I—C1-C10 alkyl, —NH—C1-C10 alkyl, —S—C1-C10 alkyl, —O-fluorinated C1-C10 alkyl, —NH-acyl, —NH—C(O)—NH-alkyl, —C—(O)—NH-alkyl, with the proviso that at least one of R3 is not H.

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