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US Patent 10035785 Phosphoinositide 3-kinase inhibitors

Patent 10035785 was granted and assigned to Karus Therapeutics on July, 2018 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Karus Therapeutics
Karus Therapeutics
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Current Assignee
Karus Therapeutics
Karus Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
100357850
Patent Inventor Names
Franck Alexandre Silva0
Stephen Joseph Shuttleworth0
Date of Patent
July 31, 2018
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Patent Application Number
154965110
Date Filed
April 25, 2017
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Patent Citations Received
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US Patent 11779586 Compounds comprising tricyclic heterocyclic compounds
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US Patent 10501478 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
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US Patent 10513530 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
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US Patent 10668077 Compositions comprising phosphoinositide 3-kinase inhibitors and a second antiproliferative agent
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US Patent 11291669 Compositions comprising phosphoinositide 3-kinase inhibitors and a second antiproliferative agent
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US Patent 11708378 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
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US Patent 10377764 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
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US Patent 10442815 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
Patent Primary Examiner
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Rebecca L Anderson
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Patent abstract

A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R and R6 are each independently (LQ)mY; R4 is H, halogen, optionally substituted aryl or optionally substituted alkyl; and; each X is independently CR7 or N. The compounds are PI3K inhibitors and therefore have potential utility in therapy.

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