Patent 10238749 was granted and assigned to Alnylam Pharmaceuticals on March, 2019 by the United States Patent and Trademark Office.
The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the angiotensinogen (AGT) gene, and methods of using such RNAi agents to inhibit expression of AGT and methods of treating subjects having an AGT-associated disorder, e.g., hypertension.