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US Patent 11040057 Pharmaceutical compositions and methods for potentiating gene silencing

Patent 11040057 was granted and assigned to OliX Pharmaceuticals on June, 2021 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
OliX Pharmaceuticals
OliX Pharmaceuticals
Current Assignee
OliX Pharmaceuticals
OliX Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11040057
Date of Patent
June 22, 2021
Patent Application Number
16313754
Date Filed
June 29, 2017
Patent Citations
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US Patent 10125362 RNA-interference-inducing nucleic acid molecule able to penetrate into cells, and use therefor
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US Patent 10214744 Nucleic acid molecules inducing RNA interference, and uses thereof
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US Patent 10238749 Angiotensinogen (AGT) iRNA compositions and methods of use thereof
Patent Primary Examiner
‌
Sean McGarry
Patent abstract

In various aspects and embodiments, the invention provides compounds or agents that potentiate siRNA cellular entry or activity, and provides methods for identifying such compounds or agents. Exemplary agents that act as L-type calcium channel blockers are described herein, and are shown to potentiate gene silencing with cp-asiRNAs.

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