Physical Sciences Inc. SBIR Phase I Award,

Physical Sciences Incproposes to develop and pre clinically validate a smart biopsy system using a multicore needlewhich is intended to substantially improve sampling efficacy and adequacy in percutaneous core needle biopsy proceduresThe custom design of the needle will allow for threading an optical probe through the bore of the needle to investigate the heterogeneity and the pH of the tissue before collecting the biopsy specimensThe new smart biopsy multicore needle will enable the interventional radiologist to make an informed decision about choosing the best area of the tumor from which a biopsy core should be sampledThe real time information provided by the optical probe will be presented in a manner that is easy to comprehendbar chart of tissue compositionwithout distracting radiologist s attention from the biopsy procedureThe preliminary evaluation of this technology will be performed in Phase I on a rabbit model of soft tissue cancerwhile in Phase II the technology will be further improved and tested on animal models of several types of cancersuch as liverlungsand brain