Neurobehavioral Research, Inc. SBIR Phase I Award, September 2019

ABSTRACT This SBIR effort is based on the idea that changes in successful Long Term AbstinenceLTAfrom alcoholism and drugs should inform treatmentOver the lastyearsour laboratory has shown adaptive changes in resting state brain network synchrony in LTA that more than reverses network synchrony differencesi eincreased appetitive drive network synchrony and decreased inhibitory control network synchronythat were associated with the development of alcohol dependenceThis Phase I SBIR attempts to implement real time EEG network synchrony neurofeedback to mimics the changes that normally occur with abstinence to support individuals efforts to achieve and maintain abstinenceThis Phase I effort will determine whether such neurofeedback can possibly increase inhibitory control network synchrony within and across dayspotentially leading to an EEG network synchrony neurofeedback treatment for alcoholism and drug addiction PROJECT NARRATIVE This SBIR effort is based on the idea that changes in successful Long Term AbstinenceLTAfrom alcoholism and drugs should inform treatmentOver the lastyearsour laboratory has shown adaptive changes in resting state brain network synchrony in LTA that more than reverses network synchrony differencesi eincreased appetitive drive network synchrony and decreased inhibitory control network synchronythat were associated with the development of alcohol dependenceThis Phase I SBIR implements real time EEG network synchrony neurofeedback and determines whether such neurofeedback can increase inhibitory control network synchrony within and across dayspotentially leading to a neurofeedback treatment for alcoholism and drug addiction