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Metabolism of the Insecticide Permethrin

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Contents

clinicaltrials.gov/study/NCT00572884
Is a
‌
Clinical study
0

Clinical Study attributes

NCT Number
NCT005728840
Health Conditions in Trial
Metabolism
Metabolism
0
Pharmacokinetics
Pharmacokinetics
0
Trial Recruitment Size
60
Trial Sponsor
University of California, Davis
University of California, Davis
0
Trial Collaborator
U.S. Army Medical Research and Development Command
U.S. Army Medical Research and Development Command
0
Clinical Trial Start Date
2006
0
Study Completion Date
2007
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Basic Science0
Interventional Trial Phase
Not Applicable0
Official Name
CCRC:Identification and Development of Biological Markers of Human Exposure to the Insecticide Permethrin0
Last Updated
December 13, 2007
0
Allocation Type
NA0
Intervention Model
Single Group Assignment0
Masking Type
None (Open Label)0
Study summary

Military personnel are exposed to the insecticide permethrin when using the DOD Insect Repellent System. A urinary metabolite of permethrin that is in high abundance and is relatively stable may be an ideal biomarker of exposure to this pesticide. Monitoring such a biomarker can prevent over-exposure. The objectives are to identify the most abundant human urinary metabolite following dermal exposure; to utilize this information to develop rapid laboratory-based and field portable methods to monitor the degree of an individual's exposure to permethrin.

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