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Kenneth R Horlick

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Megan Gustafson
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Patent primary examiner of
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US Patent 11168318 Systems and methods for rapid nucleic acid extraction, purification and analysis from bone and tooth
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US Patent 7087383 Nucleic acid sequences showing enhanced expression in benign neuroblastoma compared with acritical human neuroblastoma
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US Patent 7087414 Methods and devices for multiplexing amplification reactions
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US Patent 7090977 Electrochemiluminescence detection method for nucleic acid using intercalator and transition metal complex
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US Patent 7090978 Identification of neoplasms by detection of genetic insertions and deletions
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US Patent 7097978 Screening methods based on isolating a collection of polynucleotides corresponding to accessible regions of chromatin
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US Patent 7097980 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
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US Patent 7101663 PCR method
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US Patent 7101673 Method for detecting a nucleic acid comprising asymmetrical amplification
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US Patent 7105298 Serial coupling of restriction cleavage and extension for nucleic acid amplification
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US Patent 7108968 Mycobacterial rpoB sequences
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US Patent 7108980 Methods for the analysis of microcolonies of bacteria and yeast
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US Patent 7112405 Compositions and methods for enhancing oligonucleotide-mediated gene alteration
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US Patent 7115365 Method of analyzing a target nucleic acid
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US Patent 7115371 Rapid, sensitive and quantitative methods for tissue and cell-based proteomics via consecutive addition of quantifiable extenders
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US Patent 7115376 Method for distinguishing different-sequence polynucleotides
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US Patent 7118861 DNA detector based on molecular controlled semiconductor resistor
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US Patent 7118867 Quantitative multiplex PCR with high dynamic range
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US Patent 7118870 Detection of fecal contamination using nucleic acid molecules that recognize bacterial 16S rDNA sequences
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US Patent 7122310 Methods of constructing self-assembly of probes and method of detecting the same
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US Patent 7122313 Methods and kits for identifying and quantifying RNAs and DNAs associated with RNA and DNA binding proteins
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US Patent 7122314 Methods for detecting vancomycin-resistant microorganisms and compositions therefor
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US Patent 7122317 Multiplex method of detecting sequence-specific DNA binding proteins using detection duplexes comprising unmodified nucleic acid sequences as capture tags
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US Patent 7122355 Composition and method for hot start nucleic acid amplification
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US Patent 7125662 Method of identifying putative antibiotic resistance genes
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US Patent 7125671 Nucleic acid amplification with terminal-phosphate labeled nucleotides
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US Patent 7129045 Methods of detecting polynucleotide kinase and its use as a label
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US Patent 7129048 Loop probe hybridization assay for polynucleotide analysis
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US Patent 7129050 Method for distinguishing different-sequence polynucleotides
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US Patent 7129051 Tissue analysis and kits therefor
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US Patent 7132236 Composition and method for optimized hybridization using modified solutions
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US Patent 7132238 Method of determining a chemotherapeutic regimen based on ERCC1 expression
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US Patent 7132240 Use of methylated nucleic acid segments for isolating centromere DNA
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US Patent 7132265 Circular site-directed mutagenesis
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US Patent 11174503 Systems and methods for combined detection of genetic alterations
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US Patent 7135293 Method of detecting a nucleic acid using a fluorescent group-containing carbodiimide as a label
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US Patent 7135310 Method to amplify variable sequences without imposing primer sequences
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US Patent 7141371 Methods for detecting and localizing DNA mutations by microarray
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US Patent 7141377 Process for discrimination of nucleic acid sequence variants
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US Patent 7141398 Methods for recycling mRNA for linear cRNA amplification
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US Patent 7148008 Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
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US Patent 7153655 Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
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US Patent 7153673 Microfluidic devices and methods for performing temperature mediated reactions
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US Patent 7157232 Method to detect the end-point for PCR DNA amplification using an ionically labeled probe and measuring impedance change
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US Patent 7160680 Mutation analysis by mass spectrometry using photolytically cleavable primers
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US Patent 7160997 Methods of using FET labeled oligonucleotides that include a 3′→5′ exonuclease resistant quencher domain and compositions for practicing the same
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US Patent 7160998 Monitoring amplification with fret probes
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US Patent 7163792 Compositions and methods for optimized hybridization using modified solutions
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US Patent 7166432 Compositions and methods for genetic analysis
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US Patent 7166434 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
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US Patent 7175982 Method for the characterization of nucleic acid molecules involving generation of extendible upstream DNA fragments resulting from the cleavage of nucleic acid at an abasic site
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US Patent 7175984 Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding and development of a non-simian recombinant cell line for propagation of the virus and a target for a novel class of antiviral compounds
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US Patent 7176002 Universal-tagged oligonucleotide primers and methods of use
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US Patent 7176003 Method for determining the length of a nucleic acid molecule
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US Patent 7176004 Circular site-directed mutagenesis
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US Patent 7179603 Detection and identification of enteric bacteria
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US Patent 7183052 Methods for detection of a target nucleic acid using multi-subunit probes
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US Patent 7183053 Methods for detecting papillomavirus DNA in blood plasma and serum
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US Patent 7183084 Method for the determination of a nucleic acid using a control
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US Patent 7189508 Methods for detection of a target nucleic acid by capture using multi-subunit probes
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US Patent 7189512 Methods for variation detection
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US Patent 7189514 Cotton event PV-GHGT07(1445) and compositions and methods for detection thereof
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US Patent 7192700 Methods and compositions for conducting primer extension and polymorphism detection reactions
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US Patent 7192703 Biomolecule analysis by rolling circle amplification and SERS detection
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US Patent 7192707 Methods for analyzing polynucleotide targets using tethered oligonucleotide probes
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US Patent 7192745 Method for the determination of a nucleic acid using a control
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US Patent 7198893 DNA diagnostics based on mass spectrometry
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US Patent 7198895 In vitro cell-based methods for biological validation and pharmacological screening of chemical entities and biologicals
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US Patent 7202028 Methods for the electrochemical detection of multiple target compounds
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US Patent 7202036 Quenching methods for background reduction in luminescence-based probe-target binding assays
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US Patent 7205104 Identification of biological (micro) organisms by detection of their homologous nucleotide sequences on arrays
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US Patent 7205106 Association of polymorphisms in IL4-related genes with autoimmune disease
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US Patent 7205128 Method for synthesis of the second strand of cDNA
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US Patent 7208270 Method for diagnosing a person having multiple sclerosis
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US Patent 7208275 Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
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US Patent 7211382 Primer extension using modified nucleotides
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US Patent 7214485 Nested methylation-specific polymerase chain reaction cancer detection method
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US Patent 7214490 Method of target enrichment and amplification
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US Patent 7214522 Thermophilic DNA polymerases from
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US Patent 7216792 Self assembled nano-devices using DNA
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US Patent 7217516 Methods and kits comprising AFLP primers, and ramp primers with a part complementary to a compound microsatellite repeat and an anchor part complementary to nucleotides adjacent to the repeat
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US Patent 7223538 Post-synthesis labeling of nucleic acids, assays using nucleic acids that are labeled post-synthetically, single nucleotide polymorphism detection, and associated compounds and microarrays
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US Patent 7223544 Nucleic acid-engineered materials
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US Patent 7229765 Random-primed reverse transcriptase-
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US Patent 7235253 Powder containing physiologically active peptide
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US Patent 7235363 Method for the screening of α
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US Patent 7238480 Pyrophosphorolysis activated polymerization (PAP)
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US Patent 7238500 Use of predetermined nucleotides having altered base pairing characteristics in the amplification of nucleic acid molecules
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US Patent 7238530 Isolation and amplification of nucleic acid materials
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US Patent 7238794 Organic conductor
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US Patent 7244568 Isolation of nucleic acid
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US Patent 7247425 Methods to identify polynucleotide and polypeptide sequences which may be associated with physiological and medical conditions
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US Patent 7247457 Detection and identification of enteroviruses by semi-nested amplification of the enterovirus VP1 protein
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US Patent 7250259 Molecular torches and their use under strand displacement conditions
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US Patent 7252936 Method for the detection of the antibiotic resistance spectrum of Mycobacterium species
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US Patent 7252947 Molecular torches and their use under denaturing conditions
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US Patent 7252948 Chip-based speciation and phenotypic characterization of microorganisms
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US Patent 7252966 EG307 polynucleotides and uses thereof
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US Patent 7262012 Method for in vitro molecular evolution of protein function using varied exonuclease digestion in two polynucleotide populations
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US Patent 7262032 Allele-specific mutation detection assay using an enzyme-disabling agent
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US Patent 7264930 Processes for non-linearly amplifying nucleic acids
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US Patent 7267945 Methods of determining the presence of polynucleotides employing amplification
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US Patent 7270981 Recombinase polymerase amplification
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US Patent 7270983 Messenger RNA profiling: body fluid identification using multiplex reverse transcription-polymerase chain reaction (RT-PCR)
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US Patent 7273701 Compositions and methods for genetic analysis of polycystic kidney disease
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US Patent 7273730 Nested PCR employing degradable primers
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US Patent 7276597 Compositions and kits for detection of a nucleic acid by sequential amplification
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US Patent 7279278 Orientation-directed construction of plasmids
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US Patent 7279312 Nucleic acid mutation detection by analysis of saliva
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US Patent RE39885 Detection of nucleic acid amplification
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US Patent 7282335 Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
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US Patent 7285387 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7285652 Isolated nucleic acid molecule encoding the modified phytochrome A
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US Patent 7288378 Compositions and methods for TIGR genotyping assays
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US Patent 7288380 Detection of extracellular translocated tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
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US Patent 7288643 Corn event TC1507 and methods for detection thereof
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US Patent 7291472 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7294469 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7294470 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7297485 Method for nucleic acid amplification that results in low amplification bias
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US Patent 7297496 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7297498 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7297499 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7300757 Electronic systems and component devices for macroscopic and microscopic molecular biological reaction, analyses, and diagnostics
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US Patent 7309567 Method for reducing fluorescence quenching in bioassays
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US Patent 7309571 Amplification of self-ligated, circularized cDNA for expression profiling
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US Patent 7309572 Growth hormone-regulatable liver genes and proteins, and uses thereof
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US Patent 7309573 Methods for detection of a nucleic acid by sequential amplification
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US Patent 7309574 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7312039 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
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US Patent 7312053 Method and system for detection of nucleic acids
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US Patent 7316903 Detection of nucleic acid sequence variations using phase Mu transposase
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US Patent 7320865 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
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US Patent 7320866 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7320881 Rapid identification of
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US Patent 7321032 Method of detecting
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US Patent 7323310 Methods and compositions for RNA amplification and detection using an RNA-dependent RNA-polymerase
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US Patent 7329493 One-tube nested PCR for detecting
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US Patent 7332278 Assay methods for group transfer reactions
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US Patent 7332285 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
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US Patent 7332305 Genetic polymorphism in the Zf9 gene linked to inappropriate scarring or fibrosis
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US Patent 7332306 Method of detecting pancreatic islet amyloid protein mutant gene and nucleic acid probe and kit therefor
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US Patent 7332590 Molecular characteristics of non-small cell lung cancer
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US Patent 7335757 Carbonyl reductase, gene encoding the same, and process for producing optically active alcohols using the same
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US Patent 7338797 Compositions for isolating a cDNA encoding a membrane-bound protein
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US Patent 7341831 Method for immuno-detection of epitopes
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US Patent 7344836 Method for nucleic acid hybridization using back and forth flow between a denaturation channel and a hybridization channel via a connection channel
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US Patent 7344840 Tissue analysis and kits therefor
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US Patent 7348150 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7351534 Gene mutation associated with age-related macular degeneration
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US Patent 7351539 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7351557 Amplification of RNA sequences using composite RNA-DNA primers and strand displacement
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US Patent 7354717 Methods and kits for amplification of RNA sequences using composite primers
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US Patent 7355038 Phase isolation process for biomacromolecule components
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US Patent 7358047 Methods of forming circular nucleic acid probes and uses thereof
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US Patent 7361464 Method, systems and kits for immuno-detection of epitopes expressed on molecules
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US Patent 7361465 Methods and compositions for tailing and amplifying RNA
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US Patent 11180794 Methods and compositions for capping nucleic acids
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US Patent 11180804 In situ ATAC sequencing
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US Patent 7364846 Gene expression profiling from FFPE samples
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US Patent 7364854 Nucleotide mixture for improved nucleic acid amplification performance
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US Patent 7364858 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
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US Patent 7364895 Bioarray chip reaction apparatus and its manufacture
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US Patent 7368233 Methods of screening for lung neoplasm based on stool samples containing a nucleic acid marker indicative of a neoplasm
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US Patent 7368234 Physical mapping method using molecular combing technique allowing positioning of a great number of clones within a genome
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US Patent 7368241 Cotton event PV-GHBK04 (757) and compositions and methods for detection thereof
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US Patent 7371519 Methods and kits for indirect labeling of nucleic acids
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US Patent 7371544 Homogenous method for the detection of a polynucleotide, with e.g. cleavable lanthanide chelate label
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US Patent 7371545 Method for determining the amount of template nucleic acid present in a sample
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US Patent 7371811 Schizophrenia associated genes, proteins and biallelic markers
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US Patent 7374883 Method and kit for the detection of a novel coronoavirus associated with the severe acute respiratory syndrome (SARS)
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US Patent 7375211 Method for detection and quantification of T-cell receptor Vβ repertoire
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US Patent 7378237 Development of method for screening physiologically active pyrrole imidazole derivative
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US Patent 7378245 Methods for detecting and localizing DNA mutations by microarray
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US Patent 7381530 Kits for detection of nucleic acids by invasive cleavage
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US Patent 7381818 Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof
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US Patent 7384736 Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
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US Patent 7384739 Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
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US Patent 7384750 Nucleic acid sequences having characteristics of enhanced expression in human neuroblastoma with favorable prognosis based on comparison between human neuroblastoma with favorable prognosis and human neuroblastoma with unfavorable prognosis
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US Patent 7384769 Method for the quantitative detection of nucleic acids
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US Patent 7384770 Rapid quantification of acetic acid-producing bacteria using real-time PCR
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US Patent 7384782 Polymerase chain reaction container and process for producing the same
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US Patent 7387887 Nucleic acid melting analysis with saturation dyes
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US Patent 7390621 Methods and compositions for detecting telomerase activity
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US Patent 7390622 Apparatus and methods for detecting nucleic acid in biological samples
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US Patent 7390623 Detection and identification of
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US Patent 7393633 Genotyping kit for diagnosis of human papillomavirus infection
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US Patent 7393636 Method for forming self-assembly substance using oligonucleotide synthesized by gene amplification reaction, self-assembly substance and method for detecting gene
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US Patent 7393640 Terminal-phosphate-labeled nucleotides with new linkers
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US Patent 7393940 Screening methods and sequences relating thereto
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US Patent 7396648 Discrimination method of target base in DNA, and allele specific primer used in the method of the same
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US Patent 7399588 Method for detecting SARS coronavirus
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US Patent 7399590 Recombinase polymerase amplification
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US Patent 7399592 Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
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US Patent 7402382 GEDAP method (genotyping based on diagnostic amplification products) for detecting and/or preventing genotyping errors from amplification products of a polymorphic focus
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US Patent 7402383 Process for preparing variant polynucleotides
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US Patent 7402386 Global amplification using random priming by a composite primer
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US Patent 7402391 Method for detecting target plant genus
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US Patent 7402411 Species-specific probes for identification of target virus and identification method using said probes
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US Patent 7405041 Methods for regulating transcription by targeting quadruplex DNA
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US Patent 7405044 Multiplex PCR for simultaneous quantitation of human nuclear, mitochondrial, and male Y-chromosome DNA
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US Patent 7407748 Method and kit for the determination of cellular activation profiles
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US Patent 7407749 Method for the detection of cytosine methylations in immobilized DNA samples
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US Patent 7407782 Nucleic acid detection compositions
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US Patent 7410764 Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
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US Patent 7413855 Method for bisulfite treatment
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US Patent 7417132 Corn event TC1507 and methods for detection thereof
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US Patent 7419786 Methods for monitoring PCR amplification with fluorescently labeled probes or primers for which fluorescence changes upon hybridization to a target
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US Patent 7419787 Mass spectrometric methods for detecting mutations in a target nucleic acid
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US Patent 7419818 Organic conductor
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US Patent 7422852 Detection of nucleic acid using linear beacons
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US Patent 7425413 Methods of designing, synthesizing, and propagating reference nucleic acids
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US Patent 7425415 Method for detecting methylated CpG islands
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US Patent 7429453 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
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US Patent 7429651 Fluorescent nucleobase conjugates having anionic linkers
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US Patent 7432084 Methods for preparing nucleic acid samples
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US Patent 7432362 Assay for human DNA for gender determination
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US Patent 7435542 Exhaustive selection of RNA aptamers against complex targets
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US Patent 7435561 Methods for multiplexing recombinase polymerase amplification
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US Patent 7435807 Corn event TC1507 and methods for detection thereof
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US Patent 7435811 Method for preferentially removing protein over nucleic acids using physical as well as chemical means of removal of the protein
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US Patent 7439018 EG1117 Polynucleotides and uses thereof
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US Patent 7439021 Nucleic acid cloning
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US Patent 7439022 Nucleic acids for detection of
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US Patent 7442503 Method of treating surface of substrate used in biological reaction system
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US Patent 7442504 Herbicide tolerant cotton plants and methods for producing and identifying same
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US Patent 7442505 Compositions and methods for detecting human herpesviruses
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US Patent 7445893 Sampling method for amplification reaction analysis
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US Patent 7445898 Quantitative amplification with a labeled probe and 3′ to 5′ exonuclease activity
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US Patent 7445899 Screening method for gene variation
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US Patent 7445900 Homogeneous assay system
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US Patent 7449293 Methods and compositions for detecting
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US Patent 7449312 Kit for conducting a polymerase chain reaction
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US Patent 7449564 Corn event TC1507 and methods for detection thereof
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US Patent 7452699 Amplification of DNA in a hairpin structure, and applications
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US Patent 7459271 Method for detecting whether an organism is homozygous or heterozygous using labelled primers and RFLP
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US Patent 7462449 Methods and apparatuses for analyzing polynucleotide sequences
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US Patent 7462452 Field-switch sequencing
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US Patent 7462456 Devices for generating detectable polymers
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US Patent 7465540 Multiple reporter read-out for bioassays
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US Patent 7465561 Probes and methods for hepatitis C virus typing using single probe analysis
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US Patent 7465562 Nucleic acid processing methods, kits and devices
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US Patent 7468245 Methods for detecting nucleic acid sequences
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US Patent 7468248 Methods and systems for inferring bovine traits
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US Patent 7468249 Detection of chromosomal disorders
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US Patent 7468250 Methods and kits for screening nucleic acid duplex stability
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US Patent 7468252 Methods for tissue analysis
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US Patent 7470507 Genome-wide location and function of DNA binding proteins
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US Patent 7476501 Methods and device for DNA sequencing using surface enhanced raman scattering (SERS)
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US Patent 7476505 Devices for generating detectable polymers
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US Patent 7476733 Development of a real-time PCR assay for detection of pneumococcal DNA and diagnosis of pneumococccal disease
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US Patent 7482118 Endonuclease-substrate complexes
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US Patent 7482119 Solid phase methods for polynucleotide production
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US Patent 7485417 Post-termination labeling of nucleic acid fragments and uses thereof
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US Patent 7485418 Aberrantly methylated genes in pancreatic cancer
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US Patent 7485420 Methods and compositions for detecting colon cancers
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US Patent 7485423 Ladder assembly and system for generating diversity
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US Patent 7485428 Recombinase polymerase amplification
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US Patent 7485441 Chimeric DNA-binding proteins
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US Patent 7485443 Solid-phase reactions
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US Patent 7488575 Multidentate arrays
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US Patent 7488580 Protocol for detection of
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US Patent 7488595 Method and apparatus for amplification of nucleic acid sequences using immobilized DNA polymerase
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US Patent 7488815 Gene imprinting and methylated CpG islands
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US Patent 7491496 Method for immobilizing nucleic acid and method for manufacturing biosensor using the same method
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US Patent 7491814 Real-time RT-PCR for the sensitive detection of multiple MAGE gene transcripts
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US Patent 7494789 Methods for amplification of nucleic acid sequences using staggered ligation
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US Patent 7494790 Method of synthesizing nucleic acid
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US Patent 7498135 Method for preparing gene expression profile
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US Patent 7498136 Methods for detecting multiple species and subspecies of
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US Patent 7501237 Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
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US Patent 7501248 Prostate cancer diagnosis and outcome prediction by expression analysis
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US Patent 7501251 DNA diagnostics based on mass spectrometry
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US Patent 7501252 Use of predetermined nucleotides having altered base pairing characteristics in the amplification of nucleic acid molecules
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US Patent 7504207 Random drift mutagenesis
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US Patent 7504219 Methods and apparatus for amplification of DNA using sonic energy
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US Patent 7504221 Pyrophosphorolysis activated polymerization (PAP)
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US Patent 7504238 Processes for directionally ligating double stranded nucleic acids
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US Patent 7504240 Methods for synthesizing polynucleotides using a single primer
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US Patent 7504494 Multiplex PCR assay
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US Patent 7507529 Oligonucleotides originating from sequences coding for the surface component of PTLV envelope proteins and their uses
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US Patent 7507535 Strong PCR primers and primer cocktails
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US Patent 7510841 Methods of making and using composite arrays for the detection of a plurality of target analytes
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US Patent 7511127 Compositions, methods and systems for inferring bovine breed
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US Patent 7514212 Nucleic acid amplification using non-standard bases
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US Patent 7514220 Kits for detection of nucleic acids using invasive cleavage structures and flap endonucleases
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US Patent 7514544 Corn event TC1507 and methods for detection thereof
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US Patent 7517979 Multidentate arrays
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US Patent 7521180 Method for evaluating microsatellite instability associated with colon, gastric and/or endometrial tumors
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US Patent 7521181 Methods of diagnosing risk of myocardial infarction by detection of polymorphisms in connexin and NADH/NADPH oxidase genes
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US Patent 7521183 Method for detecting
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US Patent 7521186 PCR compatible nucleic acid sieving matrix
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US Patent 7521189 Devices for generating detectable polymers
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US Patent 7521190 Compositions and methods for genetic analysis of polycystic kidney disease
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US Patent 7521546 Branched and multi-chain nucleic acid switches for sensing and screening
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US Patent 7521547 Multiplex PCR for the detection of AmpC beta-lactamase genes
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US Patent 7524628 Method for detecting molecules expressing a selected epitope via fluorescent dyes
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US Patent 7524633 Method of detection of prostate cancer
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US Patent 7527926 Oligonucleotides, reagents and amplification methods for detecting severe acute respiratory syndrome coronavirus
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US Patent 7527930 Compositions and methods of use of standardized mixtures for determining an amount of a nucleic acid
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US Patent 7527948 Detection of HPV
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US Patent 7531306 Nucleic acid hybridization methods
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US Patent 7534567 Detection of nucleic acid sequence differences by comparative genomic hybridization
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US Patent 7534570 Method for the detection of cytosine methylations in immobilized DNA samples
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US Patent 7534588 Methods, kits and polynucleotides for simultaneously diagnosing viruses
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US Patent 7537886 Primers and methods for the detection and discrimination of nucleic acids
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US Patent 7537889 Assay for quantitation of human DNA using
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US Patent 7537895 Comparative genomic hybridization
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US Patent 7537897 Molecular counting
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US Patent 7537917 Microwave assisted PCR amplification of DNA
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US Patent 7538202 Enzyme-free isothermal exponential amplification of nucleic acids and nucleic acid analog signals
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US Patent 7541144 RNA labeling method
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US Patent 7544471 Preparing RNA from a wax-embedded tissue specimen
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US Patent 7544476 Identifying cancers sensitive to treatment with inhibitors of notch signaling
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US Patent 7544793 Making nucleic acid sequences in parallel and use
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US Patent 7547510 Thermostable proteinases from thermophilic bacteria
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US Patent 7547514 Methods for monitoring genomic DNA of organisms
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US Patent 7547516 Method for reducing the presence of amplification inhibitors in a reaction receptacle
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US Patent 7550264 Methods and kits for sense RNA synthesis
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US Patent 7550268 Rapid, sensitive and quantitative methods for tissue and cell-based proteomics via consecutive addition of quantifiable extenders
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US Patent 7550564 Method to protect DNA ends
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US Patent 7553620 Method for determining polynucleotides in a sample without attaching these to a support, and using detection probes
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US Patent 7553623 Method for detecting human papillomavirus mRNA
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US Patent 7553626 Primer set capable of specifically amplifying a target sequence found in 10 bacterial species and probe oligonucleotide specifically hybridizable with each target sequence of the 10 bacterial species
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US Patent 7553957 Methods and kits for detecting classical swine fever virus
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US Patent 7556924 Detection of nucleic acid sequence differences using coupled ligase detection with padlock probes and polymerase chain reactions
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US Patent 7560232 Methods of capturing, detecting and quantifying RNA:DNA hybrids and a modified RNase H useful therein
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US Patent 7560235 Method of detecting reaction of DNA and DNA-binding protein
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US Patent 7560253 HLS-5 tumor suppressor factor
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US Patent 7563571 MYH gene variants and use thereof
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US Patent 7563574 Methods, systems and compositions for monitoring enzyme activity and applications thereof
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US Patent 7563581 Methods for detecting and localizing DNA mutations by extension of differentially fragmented DNA
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US Patent 7566533 Clinically intelligent diagnostic devices and methods
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US Patent 7569345 Gene expression markers for breast cancer prognosis
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US Patent 7569349 Methods for selecting monoclonal antibody therapies using extracellular DNA
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US Patent 7569350 Methods for selecting cancer vaccine therapies using extracellular DNA
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US Patent 7572577 Methods for recovery of DNA from mRNA in ribosome display complexes
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US Patent 7572579 Screening method for a ribonuclease H inhibitor of a reverse transcriptase
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US Patent 7572581 2′-terminator nucleotide-related methods and systems
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US Patent 7572583 Selective restriction fragment amplification: fingerprinting
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US Patent 7572586 Identifying susceptibility to cardiac hypertrophy
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US Patent 7575863 Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
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US Patent 7575864 Method for the direct detection of diagnostic RNA
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US Patent 7575869 Genome wide location and function of DNA binding proteins
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US Patent 7579146 Nucleic acid cloning
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US Patent 7579151 Isolation and purification method of biomolecules using hydrogel
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US Patent 7582420 Multiplex nucleic acid reactions
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US Patent 7582433 Devices for generating detectable polymers
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US Patent 7582739 Negatively charged minor groove binders
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US Patent 7585626 Methods for nucleic acid amplification
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US Patent 7588886 Process for the enumeration and identification of microorganisms
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US Patent 7588891 Invasive cleavage of nucleic acids
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US Patent 7588892 Reagent sets and gene signatures for renal tubule injury
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US Patent 7592138 Identification of a gene expression profile that differentiates ischemic and nonischemic cardiomyopathy
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US Patent 7595163 Method for detecting SARS coronavirus
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US Patent 7595381 Method for detecting SARS coronavirus
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US Patent 7601495 Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
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US Patent 7601520 Method for rapid identification of porcine insulin-like growth factor 2 intron 7 point mutation
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US Patent 7601521 Detection of nucleic acid mutation associated with cancer by analysis of saliva
‌
US Patent 7604964 Method of determining the copy number of a nucleotide sequence
‌
US Patent 7608394 Methods and compositions for phenotype identification based on nucleic acid methylation
‌
US Patent 7615625 In vitro amplification of nucleic acid molecules via circular replicons
‌
US Patent 7618773 Headloop DNA amplification
‌
US Patent 7622250 Clinically intelligent diagnostic devices and methods
‌
US Patent 7625704 Methods and compositions for identifying bacteria associated with bacteria vaginosis
‌
US Patent 7625723 Method of detecting or quantitatively determining mitochondrial DNA 3243 variation, and kit therefor
‌
US Patent 7626001 Card domain containing polypeptides, encoding nucleic acids, and methods of use
‌
US Patent 7628961 Method and apparatus for amplification of nucleic acid sequences by using thermal convection
‌
US Patent 7629124 Real-time PCR in micro-channels
‌
US Patent 7629125 Sequential analysis of biological samples
‌
US Patent 7632642 Primers, probes and methods for nucleic acid amplification
‌
US Patent 7642053 Method and device for PCR-amplification and detection of nucleotide sequences
‌
US Patent 7645574 Methods of metallizing nucleic acid molecules and methods of attaching nucleic acid molecules to conductive surfaces
‌
US Patent 7645581 Determining nucleic acid fragmentation status by coincident detection of two labeled probes
‌
US Patent 7659100 DNA polymerase fusions and uses thereof
‌
US Patent 7662550 Assays for short sequence variants
‌
US Patent 7662554 Nucleic acid supported protein complementation
‌
US Patent 7666592 Methods for concurrent identification and quantification of an unknown bioagent
‌
US Patent 7666594 Methods for assaying a sample for an aggregant
‌
US Patent 7666598 Recombinase polymerase amplification
‌
US Patent 7667025 Articles of manufacture for detection of herpes simplex virus
‌
US Patent 7670810 Methods and compositions for whole genome amplification and genotyping
‌
US Patent 7674582 Methods for amplification monitoring and gene expression profiling, involving real time amplification reaction sampling
‌
US Patent 7674589 Methods for tissue analysis
‌
US Patent 7678541 Methods and compositions for the detection of a nucleic acid using a non-invasive cleavage reaction
‌
US Patent 7682786 Modulation of the binding properties of nucleic acid binding partners
‌
US Patent 7682792 Detection of nucleic acids from multiple types of human papillomaviruses
‌
US Patent 7687236 Fluorescent nucleobase conjugates having anionic linkers
‌
US Patent 7691576 Compartmentalized self tagging
‌
US Patent 7695906 Method for the manufacture of nucleic acid molecules
‌
US Patent 7695912 Site-specific cleavage of nucleic acids by photoreactive conjugates
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US Patent 7695914 Corn event DAS-59122-7 and methods for detection thereof
‌
US Patent 7696337 Composition kits and methods for performing amplification reactions
‌
US Patent 7700323 Method for detecting and amplifying target DNA
‌
US Patent 7704694 Method for detecting target plant genus
‌
US Patent 7704712 DNA polymerase fusions and uses thereof
‌
US Patent 7709202 Molecular characteristics of non-small cell lung cancer
‌
US Patent 7709203 Sequences diagnostic for shrimp pathogens
‌
US Patent 7709206 Compositions, methods and systems for inferring bovine breed or trait
‌
US Patent 7713697 Methods and kits for amplifying DNA
‌
US Patent 7714122 Nucleic acid molecules and kits including VP1 and VP3 nucleic acid molecules, useful for detecting and identifying enteroviruses
‌
US Patent 7718354 Methods for rapid identification of pathogens in humans and animals
‌
US Patent 7718369 Recurrent gene fusions in prostate cancer
‌
US Patent 7718373 Canola event PV-BNGT04(RT73) and compositions and methods for detection thereof
‌
US Patent 7723026 Method for investigating cytosine methylation in DNA by means of DNA repair enzymes
‌
US Patent 7727721 Hybridization chain reaction amplification for in situ imaging
‌
US Patent 7732141 Methods for evaluating drug-resistance gene expression in the cancer patient
‌
US Patent 7732143 Method for the diagnosis of genetic diseases by molecular combing and diagnostic kit
‌
US Patent 7736849 Oligonucleotides targeting the UL73 gene region and use thereof
‌
US Patent 7741028 Methods of identifying genetic markers in the human cystic fibrosis transmembrane conductance regulator (CFTR) gene
‌
US Patent 7741045 Sequential analysis of biological samples
‌
US Patent 7741046 Sequential analysis of biological samples
‌
US Patent 7741467 Non-fluorescent energy transfer
‌
US Patent 7745122 Analyzing messenger RNA and micro RNA in the same reaction mixture
‌
US Patent 7745137 Method of diagnosing risk of myocardial infarction by detection of specific gene polymorphisms
‌
US Patent 7754423 Methods for predicting the risk of diabetic nephropathy using genetic markers and arrays containing the same
‌
US Patent 7754429 Method for pair-wise sequencing a plurity of target polynucleotides
‌
US Patent 7759064 Development of PCR primers and primer mixtures for amplification of cnp60 target sequences
‌
US Patent 7759065 Mass spectrometric methods for detecting mutations in a target nucleic acid
‌
US Patent 7763427 Detection of recombinase polymerase amplification products
‌
US Patent 7763446 Chimeric DNA-binding proteins
‌
US Patent 7767390 Methods for evaluating drug-resistance gene expression in the cancer patient
‌
US Patent 7767455 Nucleus export reporter system
‌
US Patent 7771935 Evolving new molecular function
‌
US Patent 7771940 Methods of detecting a plurality of sequence specific DNA binding proteins with oligonucleotide detection duplexes
‌
US Patent 7771946 Methods, kits and compositions for single primer linear isothermal amplification of nucleic acid sequences
‌
US Patent 7771975 Polynucleotide analysis using combinatorial PCR
‌
US Patent 7785777 Diagnosis of Shwachman-Diamond Syndrome
‌
US Patent 7785787 Methods of isolating and amplifying nucleic acids using silanized solid support
‌
US Patent 7785795 Method of assaying nucleic acid using labeled nucleotide
‌
US Patent 7790374 Process for sequence saturation mutagenesis (SeSaM)
‌
US Patent 7790378 Screening methods involving the detection of short-lived proteins
‌
US Patent 7790386 None
‌
US Patent 7790388 Nucleic acid amplification method
‌
US Patent 7790395 Evaluation of diseases and conditions associated with translocated genes using plasma or serum DNA
‌
US Patent 7790441 Polymerase chain reaction kit and method of manufacturing the same
‌
US Patent 7794935 Reverse transcriptase compositions for flap-mediated detection of a target nucleic acid sequence
‌
US Patent 7799525 Methods for genome amplification
‌
US Patent RE41780 Chemical amplification based on fluid partitioning in an immiscible liquid
‌
US Patent 7803542 Signal-on architecture for electronic, oligonucleotide-based detectors
‌
US Patent 7803544 Method of detecting amplification product or target nucleic acid
‌
US Patent 7803547 COT102 insecticidal cotton
‌
US Patent 7803550 Methods of producing nucleic acid molecules comprising stem loop oligonucleotides
‌
US Patent 7803579 Process for amplifying nucleic acid
‌
US Patent 7807352 Process for producing two or more copies of nucleic acids in a library, and process for detecting or quantifiying more than one nucleic acid in a library
‌
US Patent 7807357 Cotton event PV-GHGT07(1445) and compositions and methods for detection thereof
‌
US Patent 7811766 Genetic identification and validation of
‌
US Patent 7816079 Method of DNA sequencing using cleavable tags
‌
US Patent 7816080 Identifying organisms by detecting intronic nucleic acid or encoded proteins
‌
US Patent 7820385 Method for retaining methylation pattern in globally amplified DNA
‌
US Patent 7820392 Cotton event PV-GHGT07(1445) and compositions and methods for detection thereof
‌
US Patent 7829280 Process for reducing interferences in luciferase enzyme assays
‌
US Patent 7829287 Method of generating branched and multi-chain nucleic acid switches for ligand detection
‌
US Patent 7833708 Nucleic acid amplification using microfluidic devices
‌
US Patent 7833713 Mitigation of Cot-1 DNA distortion in nucleic acid hybridization
‌
US Patent 7833716 Tagged oligonucleotides and their use in nucleic acid amplification methods
‌
US Patent 7834168 Herbicide tolerant cotton plants and methods for producing and identifying same
‌
US Patent 7838228 Method of quantitative and/or comparative measurement of mRNA expression levels in small biological samples
‌
US Patent 7838237 Screening methods and sequences relating thereto
‌
US Patent 7842456 Reagents, kits and methods for immunodetection of epitopes on molecules
‌
US Patent 7842457 Bead emulsion nucleic acid amplification
‌
US Patent 7851154 GC tag-modified bisulfite genomic DNA sequencing for continuous methylation spectra
‌
US Patent 7862997 Primer and primer set for amplification of CEA nucleic acid, and method for assisting cancer diagnosis
‌
US Patent 7862999 Multiplex targeted amplification using flap nuclease
‌
US Patent 7867713 Polymerase chain reaction system using magnetic beads for analyzing a sample that includes nucleic acid
‌
US Patent 7871799 Sequential addition of short DNA oligos in DNA-polymerase-based synthesis reactions
‌
US Patent 7875429 Corn event DAS-59122-7 and methods for detection thereof
‌
US Patent 7883850 None
‌
US Patent 7888008 Method for the detection of cancer
‌
US Patent 7888014 Method of detecting
‌
US Patent 7888023 Corn event DAS-59122-7 and methods for detection thereof
‌
US Patent 7888109 Apparatus and methods for detecting nucleic acid in biological samples
‌
US Patent 7892732 Method of performing PCR amplification on a microarray
‌
US Patent 7892741 Methods, kits and compositions pertaining to linear beacons
‌
US Patent 7892818 Method and kit for the determination of cellular activation profiles
‌
US Patent 7893241 Articles of manufacture for detection of herpes simplex virus
‌
US Patent 7893251 Methods for selective isolation of nucleic acids from microbial cells present in samples containing higher eukaryotic cells and/or tissues
‌
US Patent 7897342 Corn event DAS-59122-7 and methods for detection thereof
‌
US Patent 7897344 Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
‌
US Patent 7897747 Method to produce single stranded DNA of defined length and sequence and DNA probes produced thereby
‌
US Patent 7901890 Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
‌
US Patent 7910302 Efficient arrays of amplified polynucleotides
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US Patent 7910354 Efficient arrays of amplified polynucleotides
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US Patent 7914986 Detection of amplicon contamination during PCR exhibiting two different annealing temperatures
‌
US Patent 7914995 Reaction mixture for pyrophosphorolysis activated polymerization (PAP)
‌
US Patent 7919235 Oligonucleotides for genotyping thymidylate synthase gene
‌
US Patent 7919253 Serial coupling of nucleic acid metabolism and extension for nucleic acid amplification
‌
US Patent 7919254 Tissue analysis and kits therefor
‌
US Patent 7931920 Method for the isolation of nucleic acids from any starting material
‌
US Patent 7932033 Corn event DAS-59122-7 and methods for detection thereof
‌
US Patent RE42325 Homogeneous multiplex hybridization analysis by color and Tm
‌
US Patent 7935480 Detection of nucleic acid mutations by detecting the presence of heteroduplexes
‌
US Patent 7935487 Method of detecting tumor-associated DNA in plasma or serum from humans without cancer
‌
US Patent 7939260 Method for making available a priming oligonucleotide
‌
US Patent 7939312 Rapid thermocycler with movable cooling assembly
‌
US Patent 7943311 Kits and method for determining the risk of adverse effects of irinotecan comprising hybridizing pairs of nucleic acid probes
‌
US Patent 7943313 Probe, probe set, probe-immobilized carrier, and genetic testing method
‌
US Patent 7943321 Rapid, sensitive and quantitative methods for tissue and cell-based proteomics via consecutive addition of quantifiable extenders
‌
US Patent 7947446 High throughput mutation screening methods and kits using a universalized approach—differential sequence fill-in (DSF)-enabled sequential adapter ligation and amplification
‌
US Patent 7947452 Oligonucleotides originating from sequences coding for the surface component of PTLV envelope proteins and their uses
‌
US Patent 7951540 Sequences diagnostic for shrimp pathogens
‌
US Patent 7951541 Assay kit for use in method of detecting a target nucleic acid
‌
US Patent 7955801 Method and apparatus for disrupting cells and purifying nucleic acid using a single chip
‌
US Patent 7955802 Systems and methods for multiplex analysis of PCR in real time
‌
US Patent 7960120 Method for pair-wise sequencing a plurality of double stranded target polynucleotides
‌
US Patent 7964350 Sample preparation for in situ nucleic acid analysis
‌
US Patent 7972777 Nucleic acid probe-based diagnostic assays targeting ssrA genes of prokaryotic and eukaryotic organisms
‌
US Patent 7972784 Method for quantification of methylated DNA
‌
US Patent 7972786 Detection and analysis of influenza virus
‌
US Patent 7981612 Methods of screening for supracolonic neoplasms based on stool samples containing a nucleic acid marker indicative of a neoplasm
‌
US Patent 7985550 Methods of isolating methylated CpG islands
‌
US Patent 7985553 Method for isolating cell type-specific mRNAs
‌
US Patent 7989170 Method for the detection of bacterial species of the genera
‌
US Patent 7993832 Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders
‌
US Patent 7993839 Methods and kits for reducing non-specific nucleic acid amplification
‌
US Patent 7993911 Microfluidic droplet queuing network
‌
US Patent 7998679 Devices and methods for diagnosis of susceptibility to diseases and disorders
‌
US Patent 7999095 Nucleic acid supported protein complementation
‌
US Patent 8003322 Method of amplifying a target nucleic acid by rolling circle amplification
‌
US Patent 8003329 Molecular counting by color-coded micelles
‌
US Patent 8003330 Error-free amplification of DNA for clonal sequencing
‌
US Patent 8003778 Detection of red tide organisms by nucleic acid amplification
‌
US Patent 8008019 Use of dual-tags for the evaluation of genomic variable repeat regions
‌
US Patent 8012689 Elite event A2407-12 and methods and kits for identifying such event in biological samples
‌
US Patent 8012690 Bead emulsion nucleic acid amplification
‌
US Patent 8012691 Multiplex compositions and methods for quantification of human nuclear DNA and human male DNA and detection of PCR inhibitors
Edits on 13 Dec, 2021
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US Patent 8012690 Bead emulsion nucleic acid amplification
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US Patent 8008019 Use of dual-tags for the evaluation of genomic variable repeat regions
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US Patent 8003778 Detection of red tide organisms by nucleic acid amplification
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US Patent 8003322 Method of amplifying a target nucleic acid by rolling circle amplification
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US Patent 8003330 Error-free amplification of DNA for clonal sequencing
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US Patent 8003329 Molecular counting by color-coded micelles
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US Patent 7999095 Nucleic acid supported protein complementation
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US Patent 7998679 Devices and methods for diagnosis of susceptibility to diseases and disorders
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US Patent 7993911 Microfluidic droplet queuing network
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US Patent 7993839 Methods and kits for reducing non-specific nucleic acid amplification
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US Patent 7989170 Method for the detection of bacterial species of the genera
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US Patent 7985553 Method for isolating cell type-specific mRNAs
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US Patent 7985550 Methods of isolating methylated CpG islands
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