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What is the Predictive Value of the Reflux Impact Scale

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clinicaltrials.gov/study/NCT00536328
Is a
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Clinical study
0

Clinical Study attributes

NCT Number
NCT005363280
Health Conditions in Trial
Gastroesophageal reflux disease
Gastroesophageal reflux disease
0
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Gerd
0
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Heartburn
0
Trial Recruitment Size
9380
Trial Sponsor
AstraZeneca
AstraZeneca
0
Clinical Trial Start Date
2007
0
Study Completion Date
2008
0
Clinical Trial Study Type
Observational0
Observational Study Perspective
Prospective0
Official Name
What is the Value of the Use of Validated Questionnaire (Reflux Impact Scale) for Predicting Treatment Success With PPI0
Last Updated
July 9, 2008
0
Study summary

Gastric distress is a common phenomenon in our society. Heartburn and regurgitation occur daily in about 7% of the adult population,weekly 14-20% pf the adults and monthly in 34-44% of adults. The yearly prevalence of recurrent stomach complaints are frequent reason for consulting a primary care physician and are an important reason for using OTC medication. A good diagnosis is important as functional GERD with possible complications such as strictures and Barrett's esophagus or ulcer disease with life threatening complications such as bleeding \& perforations. The clinical diagnosis of reflux disease is mainly based on symptom evaluation. This, however, is hindered by the variety of complaints with different etiology. Treatment with a proton pump inhibitor can be used to confirm the diagnosis reflux disease. A major part of the patients with acid related stomach complaints indeed will experience symptom relief after starting PPI therapy. In this view, it is important to identify these patients who will react on treatment with PPI in quick, accurate, non-invasive and cheap manner. The Reflux Impact Scale (RIS) is validated, short, self explanatory questionnaire which asks for the presence \& impact of reflux symptoms. The RIS is developed for PCP to aid in the evaluation \& selection of these patient who will profit from treatment with PPI. The aim of this present study is to determine which questions of the RIS can be predictive for reaching treatment success with PPI. Treatment success is determined by asking for patients' satisfaction \& completion of the McMaster Overall Treatment Evaluation Heartburn questionnaire.

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