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Water as Therapy in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

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Contents

clinicaltrials.gov/study/NCT00759369
Is a
‌
Clinical study
0

Clinical Study attributes

NCT Number
NCT007593690
Health Conditions in Trial
Autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease
0
Trial Recruitment Size
110
Trial Sponsor
University of Kansas
University of Kansas
0
Clinical Trial Start Date
2008
0
Primary Completion Date
2009
0
Study Completion Date
2009
0
Clinical Trial Study Type
Interventional0
Interventional Trial Purpose
Treatment0
Intervention Type
Other0
Interventional Trial Phase
Not Applicable0
Participating Facility
‌
University of Kansas Medical Center
0
Official Name
Water as Therapy in Autosomal Dominant Polycystic Kidney Disease0
Last Updated
February 27, 2012
0
Allocation Type
Non-Randomized0
Intervention Model
Single Group Assignment0
Masking Type
None (Open Label)0

Other attributes

Intervention Treatment
Water prescription0
Study summary

Autosomal dominant polycystic kidney disease (ADPKD) is the most common single gene disorder that is potentially fatal. ADPKD is caused by mutations in either of two genes (PKD1, PKD2). Cysts begin to develop primarily in renal collecting tubules in utero and continue to form and expand throughout the patient's life. One of the goals of the study is to formulate a water prescription for use in clinical trials to determine the effect of sustained water diuresis on the progression of ADPKD.

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