Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Alice M. Bennett0
Date of Patent
September 21, 2010
0Patent Application Number
118929700
Date Filed
May 5, 1999
0Patent Primary Examiner
Patent abstract
A prophylactic or therapeutic vaccine for use in protecting mammals such as humans or animals against Venezelan Equine Encephalitis virus (VEE) is described. In particular, the vaccine comprises a recombinant virus such as a recombinant vaccinia virus which is able to express the structural genes of VEE in attenuated form, which has been modified to increase the protective effect of the vaccine. This is achieved by modifying the sequence of the attenuated VEE strain and/or putting this under the control of modified promoter which increases expression from the vector. Formulations of the vaccine as well as methods of treatment using the vaccine are also described.
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