Patent RE40245 was granted and assigned to Vertex Pharmaceuticals on April, 2008 by the United States Patent and Trademark Office.
The present invention relates to compounds of the formula I:or a pharmaceutically acceptable derivative or prodrug thereof. The compounds are useful as inhibitors of bacterial gyrase activity. The present invention also relates to methods for treating bacterial infections in mammala. The present invention also relates to methods for decreasing bacterial quantity in a biological sample.