Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Muthiah Manoharan0
Phillip Dan Cook0
Date of Patent
January 9, 2007
0Patent Application Number
109253480
Date Filed
August 24, 2004
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Novel chiral compounds that mimic and/or modulate the activity of wild-type nucleic acids are disclosed. In general, the compounds are phosphorothioate oligonucleotides wherein the 5′, and the 3′-terminal internucleoside linkages are chirally Sp and internal internucleoside linkages are chirally Rp.
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