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US Patent 9976140 Microrna and uses in brown fat differentiation

Patent 9976140 was granted and assigned to Joslin Diabetes Center (company) on May, 2018 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Joslin Diabetes Center (company)
Joslin Diabetes Center (company)
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Current Assignee
Joslin Diabetes Center (company)
Joslin Diabetes Center (company)
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
99761400
Patent Inventor Names
Yu-Hua Tseng0
Hongbin Zhang0
Date of Patent
May 22, 2018
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Patent Application Number
148967870
Date Filed
June 13, 2014
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Patent Primary Examiner
‌
Amy H Bowman
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Patent abstract

This invention reveals a novel miRNA and a novel miRNA-regulated signaling network which controls brown adipogenesis and thermogenic programs, thereby providing a powerful approach for the treatment of obesity and related metabolic diseases. In this regard, the present invention is also directed towards methods of treatment of obesity and excess weight (overweight) and metabolic disorders caused by or aggravated by a subject being overweight or obese.

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