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US Patent 9938239 Method for preparing silodosin

Patent 9938239 was granted and assigned to Sandoz on April, 2018 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
Sandoz
Sandoz
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
99382390
Patent Inventor Names
D. Metkar Shashikant0
Sachin Bhuta0
Parven Kumar Luthra0
Chandrakant Abhinay0
N. Chaven Dattatraya0
Date of Patent
April 10, 2018
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Patent Application Number
149761400
Date Filed
December 21, 2015
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Patent Primary Examiner
‌
Shawquia Jackson
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Patent abstract

The present invention relates to a process for preparing silodosin with high optical purity up to 99.9% enantiomeric excess (e.e.) or above. The process makes use of a method step, in which the enantiomers contained in a racemic mixture of a compound represented by the general formula V: wherein * denotes the asymmetric center, R1 is a protecting group, and R2 is cyano or carbamoyl, are separated.

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