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US Patent 9932597 Vectors for transgene expression

Patent 9932597 was granted and assigned to Adaptimmune on April, 2018 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Adaptimmune
Adaptimmune
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Current Assignee
Adaptimmune
Adaptimmune
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
99325970
Patent Inventor Names
On Kan0
Date of Patent
April 3, 2018
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Patent Application Number
145232180
Date Filed
October 24, 2014
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Patent Citations Received
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US Patent 12123013 WPRE mutant constructs, compositions, and methods thereof
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Patent Primary Examiner
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Antonio Galisteo Gonzalez
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Patent abstract

The present invention relates to a vector system involving replacement of a Woodchuck Hepatitis Virus Post-Transcriptional Regulatory Element (WPRE) sequence with an unrelated short spacer sequence for efficient expression of nucleotides of interest in a retroviral vector system and methods of delivering and expressing nucleotides of interest to target cells.

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