US Patent 9926375 Anti-endoglin antibodies and uses thereof

Patent 9926375 was granted and assigned to Tracon Pharmaceuticals on March, 2018 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors Activity

Is a

Patent

Patent attributes

Patent Applicant

Tracon Pharmaceuticals

Current Assignee

Tracon Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

9926375

Date of Patent

March 27, 2018

Patent Application Number

15131312

Date Filed

April 18, 2016

Patent Primary Examiner

‌

Christine J. Saoud

Patent abstract

The present application relates to compositions of humanized and deimmunized anti-endoglin antibodies and antigen-binding fragments thereof. One aspect relates to antibodies having one or more modifications in at least one amino acid residue of at least one of the framework regions of the variable heavy chain, the variable light chain or both. Another aspect relates to anti-endoglin antibodies which inhibit or treat fibrosis.