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US Patent 9914725 Methods of synthesizing a difluorolactam analog

Patent 9914725 was granted and assigned to Cayman Chemical Company on March, 2018 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors

Is a

Patent

Patent attributes

Patent Applicant

Cayman Chemical Company

Current Assignee

Cayman Chemical Company

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

99147250

Patent Inventor Names

Bradlee David Germain0

Stephen Douglas Barrett0

Joseph Michael Colombo0

Adam Uzieblo0

Andriy Kornilov0

James Bernard Kramer0

Date of Patent

March 13, 2018

Patent Application Number

147755910

Date Filed

March 14, 2014

Patent Primary Examiner

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Shawquia Jackson

Patent abstract

The present invention relates to processes and intermediates for preparing compounds of formula (IA), wherein R1, R4, R5, R6, and L1 are as defined herein. Compounds of formula (IA) have been found useful as EP4 receptor agonists useful in the treatment of glaucoma, osteoporosis, neuropathic pain, and related disorders.