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US Patent 9913855 Uridine diphosphate derivatives, prodrugs, compositions and uses thereof

Patent 9913855 was granted and assigned to Tufts University School of Medicine on March, 2018 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Tufts University School of Medicine
Tufts University School of Medicine
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Current Assignee
Tufts University School of Medicine
Tufts University School of Medicine
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
99138550
Patent Inventor Names
Philip G. Haydon0
Jinbo Lee0
Date of Patent
March 13, 2018
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Patent Application Number
144321040
Date Filed
September 27, 2013
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Patent Primary Examiner
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Layla D Berry
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Patent abstract

This disclosure relates to the use of uridine diphosphate (UDP) derivatives, salts and/or prodrugs thereof for the treatment of inflammatory conditions (e.g., psoriasis) and glaucoma, to prodrugs of UDP derivatives, compositions comprising therapeutically effective amounts of those prodrugs of the UDP derivatives and methods of using those prodrugs for treating various disorders including, e.g., neuronal disorders, including neurodegenerative disorders (e.g., Alzheimer's disease, Parkinson's disease) and traumatic CNS injury, pain, Down Syndrome (DS), glaucoma, and inflammatory conditions, e.g., psoriasis and rheumatoid arthritis.

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