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US Patent 9877998 Uses of hypoxia-inducible factor inhibitors

Patent 9877998 was granted and assigned to OncoImmune on January, 2018 by the United States Patent and Trademark Office.

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Sami N. Malek0

Yin Wang0

Yang Liu0

Pan Zheng0

Yan Liu0

Date of Patent

January 30, 2018

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Patent Application Number

154487370

Date Filed

March 3, 2017

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Patent Primary Examiner

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Patent abstract

The present invention relates to treating a hematologic cancer using a Hypoxia-Inducible Factor (HIF inhibitor). The invention also relates to inducing acute myeloid leukemia remission using the HIF inhibitor. The invention further relates to inhibiting a maintenance or survival function of a cancer stem cell (CSC) using the HIF inhibitor.

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