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US Patent 9744187 p-Ethoxy nucleic acids for liposomal formulation

Patent 9744187 was granted and assigned to Bio-Path Holdings on August, 2017 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Bio-Path Holdings
Bio-Path Holdings
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Current Assignee
Bio-Path Holdings
Bio-Path Holdings
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
97441870
Patent Inventor Names
Peter Nielsen0
Date of Patent
August 29, 2017
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Patent Application Number
152942230
Date Filed
October 14, 2016
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Patent Citations Received
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US Patent 12064446 Methods and compositions for treating cancers and enhancing therapeutic immunity by selectively reducing immunomodulatory M2 monocytes
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US Patent 11801259 Methods and compositions for treating cancers using antisense
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US Patent 12012601 Combination therapy with liposomal antisense oligonucleotides
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Patent Primary Examiner
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Tracy Vivlemore
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Patent abstract

Provided herein are therapeutic oligonucleotides that comprise at least one p-ethoxy backbone linkage but no more than 80% p-ethoxy backbone linkages. Provided herein are improved delivery systems for therapeutic oligonucleotides comprising a liposome that comprises neutral phospholipids and a p-ethoxy oligonucleotide that is entrapped in the liposome.

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