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US Patent 9688985 MicroRNA compounds and methods for modulating miR-21 activity

Patent 9688985 was granted and assigned to Regulus Therapeutics on June, 2017 by the United States Patent and Trademark Office.

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Is a
Patent
Patent

Patent attributes

Patent Applicant
Regulus Therapeutics
Regulus Therapeutics
Current Assignee
Regulus Therapeutics
Regulus Therapeutics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9688985
Patent Inventor Names
Balkrishen Bhat0
Eric Marcusson0
Date of Patent
June 27, 2017
Patent Application Number
14995432
Date Filed
January 14, 2016
Patent Citations Received
‌
US Patent 12110491 Selective reduction of allelic variants
0
Patent Primary Examiner
‌
Kate Poliakova-Georgantas
Patent abstract

Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-21, and also to treat diseases associated with abnormal expression of miR-21, such as fibrosis and cancer.

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