Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Stefan H. Bossmann0
Deryl L. Troyer0
Matthew T. Basel0
Date of Patent
June 20, 2017
0Patent Application Number
146050390
Date Filed
January 26, 2015
0Patent Primary Examiner
Patent abstract
The present invention provides a diagnostic reagent or assay for assessing the activity of a protease in vivo or in vitro and methods of detecting the presence of a cancerous or precancerous cell. The assays are comprised of two particles linked via an oligopeptide linkage that comprises a consensus sequence specific for the target protease. Cleavage of the sequence by the target protease can be detected visually or using various sensors, and the diagnostic results can be correlated with cancer prognosis.
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