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US Patent 9604927 Indolinone compounds and uses thereof

Patent 9604927 was granted and assigned to Oncternal Therapeutics on March, 2017 by the United States Patent and Trademark Office.

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Current Assignee
Oncternal Therapeutics
Oncternal Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
96049270
Patent Inventor Names
Jean-Michel Vernier0
Date of Patent
March 28, 2017
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Patent Application Number
148777080
Date Filed
October 7, 2015
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Patent Primary Examiner
‌
Alicia L Otton
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Patent abstract

Indolinone derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indolinone derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.

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