Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Marc Thomas0
Chi-Fang Wu0
Darin Lee0
Jeffry D. Watkins0
John D. Mendlein0
Kristi Piehl0
Ying Buechler0
Minh-Ha Do0
...
Date of Patent
March 7, 2017
0Patent Application Number
142144910
Date Filed
March 14, 2014
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides histidyl-tRNA synthetase and Fc region conjugate polypeptides (HRS-Fc conjugates), such as HRS-Fc fusion polypeptides, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The HRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified HRS polypeptides.
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