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US Patent 9573965 Process for the preparation of Dolutegravir

Patent 9573965 was granted and assigned to Aurobindo Pharma on February, 2017 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors

Is a

Patent

Patent attributes

Patent Applicant

Aurobindo Pharma

Current Assignee

Aurobindo Pharma

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

9573965

Patent Inventor Names

Shankar Reddy Budidet0

Srinivasa Rao Yatcherla0

Sivakumaran Meenakshisunderam0

Subba Reddy Danda0

Srinivasachary Katuroju0

Gowrisankar Rao Kaki0

Jagan Mohan Reddy Sanapureddy0

Nageshwar Dussa0

Date of Patent

February 21, 2017

Patent Application Number

14888702

Date Filed

February 7, 2014

Patent Primary Examiner

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Kahsay Habte

Patent abstract

The present invention provides (R)-3-Amino-1-butanol (D)-tartarate (IIb); process for its preparation and its conversion to Dolutegravir. The present invention also provides an improved process for the preparation of Dolutegravir (I) or pharmaceutically acceptable salts wherein compound (XVI) is reacted with an optically active acid addition salt of (R)-3-amino-1-butanol (IIa).