Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
December 20, 2016
Patent Application Number
14697955
Date Filed
April 28, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention involves the use of transcription factors including Tbx5, Mef2C, Hand2, myocardin and Gata4 to reprogram cardiac fibroblasts into cardiomyocytes, both in vitro and in vivo. Such methods find particular use in the treatment of patients post-myocardial infarction to prevent or limit scarring and to promote myocardial repair.
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