Patent 9511210 was granted and assigned to The Foundry (Supernatural) on December, 2016 by the United States Patent and Trademark Office.
Apparatus for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light chain fragment toxins which lack cell binding capacity.