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US Patent 9506057 Modifications for antisense compounds

Patent 9506057 was granted and assigned to Integrated DNA Technologies on November, 2016 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Integrated DNA Technologies
Integrated DNA Technologies
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Current Assignee
Integrated DNA Technologies
Integrated DNA Technologies
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
95060570
Patent Inventor Names
Joseph Alan Walder0
Richard Owczarzy0
Mark Aaron Behlke0
Ashley Mae Jacobi0
Kimberly Ann Lennox0
Date of Patent
November 29, 2016
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Patent Application Number
137763970
Date Filed
February 25, 2013
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Patent Primary Examiner
‌
Jane Zara
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Patent abstract

The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.

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