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US Patent 9506030 Compounds and methods for enhanced cellular uptake

Patent 9506030 was granted and assigned to Regulus Therapeutics on November, 2016 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Regulus Therapeutics
Regulus Therapeutics
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Current Assignee
Regulus Therapeutics
Regulus Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
95060300
Patent Inventor Names
Balkrishen Bhat0
Date of Patent
November 29, 2016
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Patent Application Number
142661270
Date Filed
April 30, 2014
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Patent Citations Received
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US Patent 11759532 mRNA targeting molecule comprising N-acetylgalactosamine binding polypeptide and preparation method therefor
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US Patent 12005120 Galnac conjugated modified oligonucleotides as miR-122 inhibitor having HCV antiviral activity with reduced hyperbilirubinemia side-effect
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US Patent 11932857 Immunostimulatory oligonucleotides
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US Patent 11707528 Mannose-based mRNA targeted delivery system and use thereof
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Patent Primary Examiner
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Lawrence E Crane
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Patent abstract

Described herein are conjugated modified oligonucleotides that are complementary to a target RNA. The conjugate facilitates cellular uptake of the modified oligonucleotide, resulting improved potency.

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