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US Patent 9493419 Quinoline derivatives as anti-cancer agents

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Kim Hung Lam0

Johnny Cheuk-on Tang0

Sau Hing Chan0

Albert Sun Chi Chan0

Date of Patent

November 15, 2016

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Patent Application Number

133340730

Date Filed

December 22, 2011

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Patent Citations Received

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US Patent 11753413 Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors

US Patent 11767323 Tricyclic pyridone compounds as JAK2 V617F inhibitors

US Patent 11780840 Tricyclic urea compounds as JAK2 V617F inhibitors

US Patent 11919908 Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors

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US Patent 11958861 Spirocyclic lactams as JAK2 V617F inhibitors

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Patent Primary Examiner

Timothy R Rozof

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Patent abstract

Quinoline derivatives showing anticancer activities against cancer cell lines of hepatocellular carcinoma (Hep3B), lung carcinoma (A549), esophageal squamous cell carcinoma (HKESC-1, HKESC-4 and KYSE150). The quinoline derivatives have a backbone structure of the following formulas:

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