Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
James A. Williams0
Aaron E. Carnes0
Date of Patent
November 8, 2016
0Patent Application Number
146129600
Date Filed
February 3, 2015
0Patent Primary Examiner
Patent abstract
General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.
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